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Saturday, April 10, 2021

St. Joseph Catholic School Athletic Complex

Walk-in Moderna Covid vaccines today! No appointment needed. 60 of 200 doses administered so far. Don't let them go to waste, folks. https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD

Thursday, March 11, 2021

Convalescent Plasma Strikes Out As COVID-19 Treatment

Convalescent Plasma Not Beneficial as Covid-19 Treatment No surprise really. It was a hope and prayer treatment at the onset of the pandemic one year ago because we had no other options. We knew convalescent plasma was not beneficial for other recent viral epidemics like the Ebola virus. -Keep masking -Get a vaccine Things will get better. https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD

Friday, March 5, 2021

Pandemic-onomics: Lessons From The Spanish Flu : The Indicator from Planet Money

Should You Still Wear a Mask? Starting March 10: -All Texas businesses can open without limits on capacity or occupancy. -There will no longer be a statewide mandate to wear face coverings in public places. I would urge those in the Brazos Valley to continue to mask up. We are not out of this pandemic. We have a while to go to immunize sufficiently for herd immunity. Plus, if our community masks up, we are likely to come out ahead economically. Listen: https://ift.tt/38d0CMu https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD

Friday, February 26, 2021

CDC Launches Web Tool To Help Americans Find COVID-19 Vaccines

Find Covid Vaccines in your area with VaccineFinder.org Also, register at your county's or region's vaccine hub: https://ift.tt/39Hw07f VaccineFinder: https://ift.tt/3sqEs1i https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD

Saturday, February 20, 2021

FDA issues alert on the 'limitations' of pulse oximeters

Pulse oximeters do have shortcomings. Some are quite insensitive. They may be affected by nail polish and by skin color. They may be prone to motion and low blood pressure artifacts leading to inaccurate readings. I do not routinely recommend them even for those with chronic lung conditions because they tend to cause more anxiety than assistance and they do not necessarily beget a change in therapy. The gold standard is the direct measurement of the dissolved oxygen content in your arterial blood (requires a needle stick). A common misconception is that shortness of breath is primarily due to low oxygen levels. In many instances of shortness of breath, however, the oxygen levels are just fine. If you are going to use such devices. Get a reliable one with a high degree of specificity and sensitivity. Test after you have been still/resting for at least two minutes. Reference: J Clin Anesth. 2012 Aug;24(5):385-91. doi: 10.1016/j.jclinane.2011.10.012. Epub 2012 May 22. Performance of three new-generation pulse oximeters during motion and low perfusion in volunteers. Shah N1, Ragaswamy HB, Govindugari K, Estanol L. https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD

Friday, February 5, 2021

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

Sputnik V Covid Vaccine As published in The Lancet, the interim analysis of the phase 3 trial of Gam-COVID-Vac showed 91·6% efficacy against COVID-19. The scientists used adenovirus vectors, rAd 26 and rAd5, to deliver a Covid viral antigen to the immune system for recognition and immune response. Adenoviruses are among the common cold virus. So, in essence, they used a common cold virus to deliver a payload to our bodies. It's a clever approach because adenoviruses are well adapted to infecting the respiratory tract. Using one virus as a vector to deliver a payload is a known technique. For example, using the poliovirus as a vector to deliver anti-cancer treatment for recurrent glioblastoma (a type of brain tumor). It will be curious to see how well the immune response holds up for different age and health risk demographics over time. The human immune system is quite familiar with many strains of adenoviruses so we may have circulating antibodies against the adenovirus vectors which may make the immunogenic response variable in some hosts and variable over time. The same holds true for all of the authorized Covid vaccines. It will be interesting to see how the immunity holds up over time. https://ift.tt/1VMjaZw
from Rajesh Harrykissoon, MD